General description
Proopiomelanocortin (POMC) is a pro-peptide and multifunctional precursor protein for melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone ACTH. The POMC gene is mapped to human chromosome 2p23.3. It is expressed in skin, pituitary gland, and tissues of the immune system.
Immunogen
Peptide with sequence C-NAIIKNAYKKGE from the C Terminus of the protein sequence according to NP_000930.1; NP_001030333.1.
Biochem/physiol Actions
Proopiomelanocortin (POMC) expression is regulated by hypermethylation of the upstream CpG-rich island in the gene. Mutations in the POMC gene are implicated in adrenocorticotropic hormone (ACTH) deficiency. Adrenal insufficiency and obesity are correlated to loss of function mutations in POMC.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Shipping Information:
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- UPC:
- 51183619
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- SAB2500826-100UG
- Temperature Control Device:
- Yes
