Anti-Protocadherin 19 Antibody (C15-1318-047)

General description

Protocadherin-19, also known as Potential calcium-dependent cell-adhesion protein (PCDH19), is a single-pass type I membrane protein that is moderately expressed in all regions of the brain and ovary, and has low expression in other tissues. Defects in PCDH19 cause epileptic encephalopathy, early infantile type 9 (EIEE9), also known as epilepsy female-restricted with mental retardation.

Immunogen

Epitope: Cytoplasmic domain

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Protocadherin 19.

Application

Detect Protocadherin 19 using this Anti-Protocadherin 19 Antibody validated for use in IHC (Paraffin).

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected Protocadherin 19 in mouse hypothalamus and hind brain tissues, whereas a 1:2,000 dilution from a representative lot detected Protocadherin 19 in human cerebellum tissue.

Research Category
Cell Structure

Research Sub Category
Adhesion (CAMs)

Quality

Evaluated by Immunohistochemistry in human cerebral cortex tissue.

Immunohistochemistry Analysis: A 1:500 dilution of this antibody detected Protocadherin 19 in human cerebral cortex tissue.

Target description

126 kDa calculated

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: human, mouse. technique(s): immunohistochemistry: suitable (paraffin). NCBI accession no.: NP_065817. UniProt accession no.: Q8TAB3. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... PCDH19(57526). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.