General description
Immunoglobulin G (IgG) is made up of four polypeptide chains: two heavy chains (γ chains) and two light chains (κ or λ chains) which are inter linked by disulfide bonds. The Fab (fragment antigen binding) arm of IgG is formed by the VH and CH1 domains of the heavy and the light chains. The V regions of the antibody serve as the antigen-binding region. IgG class of immunoglobulins consists of four sub-classes i.e IgG1, IgG2, IgG3, and IgG4.. T
Biochem/physiol Actions
IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Immunoglobulin G (IgG) is a group of antibodies that are involved in modulating various immune responses. IgG activates the complement system and regulates the antibody-dependent cell-mediated cytotoxicity (ADCC).
Physical form
Rabbit Anti-Rat IgG is supplied as a liquid containing 0.1% sodium azide (see MSDS) as preservative.
Preparation Note
treated to remove lipoproÂÂteins
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Shipping Information:
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- UPC:
- 41181529
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- R5381-2ML
- Temperature Control Device:
- Yes
