ANTI-RB ANTIBODY PRODUCED IN RABBIT

Catalog No.: C005B-319311
Mfr. No.: SAB5700023-100UL
Mfr. Name: Sigma-Aldrich
Qty/UOM: 1
UOM: EA

Price: $757.80

List Price: $842.00

General description The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin

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Description
Specifications

General description

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

Immunogen

Recombinant protein of human RB1.

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20Ã¢â€žÆ’. Avoid freeze / thaw cycles.

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UPC:: 51112023
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SAB5700023-100UL
Temperature Control Device:: Yes

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