Immunogen
Immunogen Sequence: GI # 4506513, sequence 130-202
Recombinant regulator of G-protein signalling 16
Application
Anti-RGS16 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
Regulator of G-protein signaling 16 is a protein encoded by the RGS16 gene in humans and is mapped to chromosome 1q25-1q31. It is found to be expressed in 17 human gastrointestinal cancer cell lines. RGS16 expression is higher in colorectal cancer (CRC) tissue when compared to normal tissue. It can act as a predictive marker for patient prognosis of CRC. Loss of RGS16 in some breast tumors enhances PI3K signaling elicited by growth factors and thereby promotes proliferation and TKI evasion downstream of HER activation.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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- UPC:
- 51173230
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- GW21321-50UG
- Temperature Control Device:
- Yes
