General description
RSV is a labile paramyxovirus that produces a characteristic fusion of human cells in tissue culture--the syncytial effect. Two subtypes, A and B, have been identified. Subtype B are characterized as the asymptomatic strains of the virus. The more severe clinical illnesses involve Subtype A strains.
Specificity
Reacts with RSV fusion protein, specifically epitope F1a of RSV F-protein {Sominina AA, et al Vestn Ross Akad Med Nauk. 1995;(9):49-54} found on all A & B strains of RSV.
Immunogen
A2 RSV virus cell extract
Epitope: all type A & B strains
Application
Anti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A detects level of Respiratory Syncytial Virus & has been published & validated for use in ELISA, FC, IF & WB.
Indirect immunofluorescence.
ELISA
Immunoblotting: (using purified F protein preparations, clone identified a ~70kDa band, Tripp, RA et al 2003)
Final working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Target description
~70 kDa
Physical form
Format: Purified
Protein A Purified immunoglobulin in 0.02M phosphate, 0.25M NaCl, 0.1% NaN3 pH 7.6
Protein A purified
Storage and Stability
Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
RSV Control Slides, Catalogue Number 5012-5
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Shipping Information:
Dry Ice Surcharge & Ice Pack Shipments: $40
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- UPC:
- 41202050
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- MAB8599
- Temperature Control Device:
- Yes
