ANTI-SAPAP2 ANTIBODY (C15-1317-561)

General description

SAP90/PSD-95-associated protein 2 (SAPAP2, also known as DLGAP2) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP2 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2).

Specificity

At least three isoforms of SAPAP2 are known to exist. This SAPAP2 antibody will not cross-react with other SAPAP proteins.

Immunogen

KLH-conjugated linear peptide corresponding to human SAPAP2.

Application

Immunohistochemistry Analysis: 5 µg/mL of this antibody from a representative lot detected SAPAP2 in human brain tissue.

Research Category
Neuroscience

Research Sub Category
Synapse & Synaptic Biology

This SAPAP2 antibody is validated for use in WB & IHC for the detection of the SAPAP2 protein.

Quality

Evaluated by Western Blot in L1210 cell lysate.

Western Bloting Analysis: 1 µg/mL of this antibody detected SAPAP2 in 15 µg of L1210 cell lysate.

Target description

~114 kDa observed. Uncharacterized bands may be observed.

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS and 0.02% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
L1210 cell lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: mouse, human. technique(s): immunohistochemistry: suitable, western blot: suitable. UniProt accession no.: Q9P1A6. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... DLGAP2(9228). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.

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