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ANTI-SIRT5 ANTIBODY PRODUCED IN CHICKEN

Catalog No.
C15-1741-093
Mfr. No.
SAB3500496-100UG
Mfr. Name
Sigma-Aldrich
Qty/UOM
1
UOM
EA
Price: $980.46
List Price: $1,089.40

General description SIRT5 (Sirtuin 5) is a mitochondrial matrix protein belonging to the class III of the sirtuin family. It is localized inside the mitochondria and within the cytosol and nucleus.

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General description

SIRT5 (Sirtuin 5) is a mitochondrial matrix protein belonging to the class III of the sirtuin family. It is localized inside the mitochondria and within the cytosol and nucleus. The protein is widely expressed in the brain, heart, liver and kidney. It is composed of very short amino and carboxyl terminal sequences flanking region with the conserved, catalytic sirtuin center domain.

Immunogen

SIRT5 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human SIRT5.

Application

Anti-SIRT5 antibody produced in chicken is suitable for western blot and indirect ELISA.

Biochem/physiol Actions

SIRT5 (Sirtuin 5) is associated with metabolism and aging process. It has been reported in a study that SIRT5 influences urea cycle pathway by NAD-dependent deacetylation and subsequent activation of carbamoyl phosphate synthetase 1 (CPS1), which plays a vital role in the initial step of urea cycle for the detoxification and removal of ammonia. In non-small cell-lung cancer cells. SIRT5 contributions have also been observed for the cancer cell growth and drug resistance. Study shows that SIRT5 may possess oncogenic property.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500496.

Physical form

Supplied in PBS with 0.02% sodium azide.

Shipping Information:

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UPC:
41116012
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
SAB3500496-100UG
Temperature Control Device:
Yes

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