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ANTI-SLBP ANTIBODY

Sigma Aldrich

Catalog No.
C15-1616-493
Manufacturer No.
06-1376
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
EA
Price: $829.44
List Price: $921.60

General description The SLPB gene (stem-loop binding protein) encodes a protein that binds to the stem-loop structure of replication-dependent histone pre-mRNAs. Histone mRNA lack a polyadenylation signal.

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General description

The SLPB gene (stem-loop binding protein) encodes a protein that binds to the stem-loop structure of replication-dependent histone pre-mRNAs. Histone mRNA lack a polyadenylation signal. Consequently, the interaction of this protein with histone pre-mRNA contributes to efficient 3′ end processing by stabilizing the complex between the pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP). Expression of this protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.

Specificity

Antibody recognizes SLBP.

Immunogen

KLH-conjugated linear peptide corresponding to the C-terminus of human SLBP.

Application

Immunocytochemistry:
Representative lot data.
Confocal fluorescent analysis of NIH/3T3 cells using 06-1376 (Red). Actin filaments have been labeled with AlexaFluor488 -Phalloidin (Green). Nucleus is stained with DAPI (Blue). This antibody positively stains cytoplasm and nucleus.

Research Sub Category
RNA Metabolism & Binding Proteins

Histones

Use Anti-SLBP Antibody (Rabbit Polyclonal Antibody) validated in WB, ICC to detect SLBP also known as Histone stem-loop-binding protein, HBP, Histone RNA hairpin-binding protein.

Quality

Evaluated by Western Blotting in C2C12 cell lysates.

Western Blotting Analysis: A 1:1000 dilution of this antibody detected SLBP in C2C12 cell lysates.

Target description

38 kDa

Physical form

Serum in buffer containing 0.05% sodium azide

Analysis Note

Control
C2C12 cell lysates.

UPC:
51202401
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
06-1376
Product Size:
1376

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