ANTI-STAPHYLOCOCCUS AUREUSSTAPH 11-248.2

General description

Staphylococcus aureus is cocci-shaped Gram-positive bacteria that is the causative agent of multiple human infections, including bacteremia, infective endocarditis, skin and soft tissue infections. Although S. aureus is not always pathogenic but is a common cause of skin infections such as abscesses, respiratory infections, and food poisoning. Pathogenic strains often promote infections by producing potent protein toxins and expressing cell-surface proteins that bind and inactivate antibodies. Its mechanisms for evasion of the host immune response include the production of an antiphagocytic capsule, sequestering of host antibodies or antigen masking by Protein A, biofilm formation, intracellular survival, and blocking chemotaxis of leukocytes. Infection by S.aureus involves colonization, local infection, systemic dissemination and/or sepsis, metastatic infection, and toxinosis.

Specificity

Clone STAPH 11-248.2 is a mouse monoclonal antibody that specifically detects Staphylococcus aureus. It does not display any cross-reactivity with Streptococcus sp., Mycoplasma sp., or Corynebacteria sp.

Immunogen

UV-inactivated Staphylococcus aureas cells (ATCC# 29740).

Application

Anti-Staphylococcus aureus, clone STAPH 11-248.2, Cat. No. MAB930-I, is a mouse monoclonal antibody that detects Staphylococcus aureus and is tested for use in ELISA.

ELISA: (Dilution is assay based)

Note: Actual optimal working dilutions must be determined by end user as specimens, and experimental conditions may vary with the end user

Physical form

Purified mouse monoclonal in buffer containing PBS, pH 7.4, containing no preservatives.

Storage and Stability

Stable for 1 year at +2°C to +8°C from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.