General description
Synaptotagmin-7 is also referred to as Synaptotagmin VII (SytVII) and is a member of the synaptotagmin family of transmembrane transporters. Synaptotagmin-7 is involved in plasma membrane repair, and possibly Ca2+-dependent exocytosis and traffiking of secretory vesicles.
Specificity
This antibody recognizes the cytoplasmic C2A domain of Synaptotagmin-7. This antibody does not cross react with Synaptotagmin-6 or other Synaptotagmins (Prof. J. Trimmer, University of California, Davis.).
Immunogen
Epitope: Cytoplasmic C2A domain
Recombinant protein corresponding to the cytoplasmic C2A domain of mouse Synaptotagmin-7.
Application
Anti-Synaptotagmin-7 Antibody, clone N275/14 is a highly specific mouse monoclonal antibody, that targets Synaptotagmin & has been tested in western blotting & IHC.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Synaptotagmin-7 in human thalamus tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling
Quality
Evaluated by Western Blotting in mouse brain tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected Synaptotagmin-7 in 10 µg of mouse brain tissue lysate.
Target description
~ 45 kDa observed. Uncharacterized band(s) may appear in some lysates.
Physical form
Format: Purified
Protein G Purified
Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Mouse brain tissue lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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- UPC:
- 51204100
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- MABN665
- Temperature Control Device:
- Yes