General description
Syntaxin 7 is a 35kDa protein and is a member of t-Soluble N-ethylmaleimide-sensitive factor activating protein receptor (SNARE) protein family. It is widely expressed in multiple tissues.
Immunogen
synthetic peptide corresponding to amino acids 131-149 located at the mid-region of rat syntaxin 7, conjugated to KLH. This sequence is highly conserved (two amino acid substitutions) in mouse and human syntaxin 7 (~80% identity).
Application
Anti-Syntaxin 7 antibody produced in rabbit has been used in immunoblotting and immunofluorescence.
Biochem/physiol Actions
Syntaxin 7, localized on membrane compartments of late endosomes, facilitates fusion of late endosomes with lysosomes. The protein also helps in lysosomal biogenesis. Mutant syntaxin 7 lacking the transmembrane domain blocks endocytic transport from the early to late endosome. Syntaxin 7 has been described to play an important role during phagocytosis.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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- UPC:
- 12352202
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- S4819-200UL
- Temperature Control Device:
- Yes
