General description
Toll-like receptor 4 (TLR4) belongs to the interleukin-1 receptor (IL-1R) family. It is highly polymorphic and is located on human chromosome 9q33.1.
Immunogen
Antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TLR4.
Biochem/physiol Actions
Toll-like receptor 4 (TLR4) acts as the receptor for LPS (lipopolysaccharides ), a gram-negative bacterial cell wall component. Mutations in TLR4 affects mRNA and protein expression in colorectal cancer.
Features and Benefits
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Linkage
The action of this antibody can be blocked using blocking peptide SBP3500765.
Physical form
Supplied at 1 mg/mL in PBS with 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
- UPC:
- 12352203
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- SAB3500765-100UG
- Product Size:
- 100/µG