General description
Trypsin-3 is also called Brain trypsinogen, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, and Trypsin IV and belongs to the peptidase S1 family. Trypsin-3 is a digestive protease that specifically degrades trypsin inhibitors and may be involved in the processing of defensins, including DEFA5, in the ileum. Trypsin-3 is expressed in pancreas, brain and in Paneth cells, at the base of small intestinal crypts.
Specificity
Other homologies: Rat (82% sequence homology), Mouse (72% sequence homology).
Immunogen
KLH-conjugated linear peptide corresponding to the human Trypsin-3.
Application
Anti-Trypsin-3 Antibody is a highly specific rabbit polyclonal antibody, that targets Trypsin & has been tested in western blotting & IHC (Paraffin).
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Trypsin-3 in human pancreatic, cerebellum, and thalamus tissues.
Quality
Evaluated by Western Blotting in human pancreas tissue lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected Trypsin-3 in 10 µg of human pancreas tissue lysate.
Target description
~26 kDa observed. Four isoforms are known to exist due to alternative splicing.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: human. technique(s): immunohistochemistry: suitable (paraffin), western blot: suitable. NCBI accession no.: NP_031369. UniProt accession no.: P35030. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... PRSS3(5646). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 12352203
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- ABN262
