Anti-UTF1 Antibody (C15-1316-065)

General description

Undifferentiated embryonic cell transcription factor 1 is a nucleus protein encoded by the UTF1 gene in human and functions as a transcriptional coactivator of ATF2. UTF1 is reported to interact with the ATF-2 metal binding motif via the leucine zipper motif within its conserved domain 2 (CD2) and both CD1 & CD2 of UTF1 and also independently mediates association with TATA-binding protein-containing complex. (PMID 9749258)

Specificity

Other homologies: mouse, rat 95%.

Immunogen

Epitope: Near N-terminus

KLH-conjugated linear peptide corresponding to human UTF1 near N-terminus.

Application

Anti-UTF1 Antibody is an antibody against UTF1 for use in Western Blotting and Immunohistochemistry.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected UTF1 in mouse kidney and rat liver tissue.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Nuclear Receptors

Quality

Evaluated by Western Blotting in mouse embryonic stem cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected UTF1 in 10 µg of mouse embryonic stem cell lysate.

Target description

~48 kDa observed. UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells (Okuda, A., et al. (1998). EMBO. 17(7):2019–2032).

Linkage

Replaces: AB3383

Physical form

Affinity

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Other Notes

Concentration: Please refer to lot specific datasheet.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: rat, mouse. species reactivity (predicted by homology): human (based on 100% sequence homology). technique(s): immunohistochemistry: suitable, western blot: suitable. NCBI accession no.: NP_003568. UniProt accession no.: Q5T230. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... UTF1(8433). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.