General description
ANX Sepharose™ 4 Fast FLow (high sub) is a weak anion exchanger, with a different selectivity compared with traditional ion exchangers. It is optimized for the separation of larger proteins.
Application
ANX Sepharose™ Fast FLow (high sub) is part of the Sepharose™ Fast FLow ion exchange platform, which has been the industrial standard for ion exchange chromatography during recent decades. ANX Sepharose™ 4 Fast FLow (high sub) is a weak anion exchanger medium with tertiary amine groups attached to the base matrix Sepharose™ 4 Fast FLow via ether linkage and a hydrophilic spacer arm. The diethylaminopropylgroup is coupled in a mode that precludes formation of quaternary groups, which are typically seen on traditional DEAE media, resulting in a truly weak anion exchanger. The base matrix, Sepharose™ 4 Fast Flow, is a highly cross-linked, 4% Agarose derivative with high chemical and physical stability and broad separation range. ANX Sepharose™ 4 Fast FLow (high sub) has high chemical stability, allowing well proven cleaning-in-place (CIP) and sanitization protocols.
As member of the BioProcess media range, ANX Sepharose™ 4 Fast FLow (high sub) meets industrial demands with security of supply and comprehensive technical and regulatory support.
Features and Benefits
- Weak anion exchanger with different selectivity compared with traditional ion exchangers.
- Applicable for separation of high molecular weight Proteins
- Developed in co-operation with leading large-scale pharmaceutical manufacturers
- High chemical stability allows for well proven CIP and sanitization protocols
- The hydrophilic nature of the base matrix ensures Low levels of non-specific binding leading to Low levels of host cell-derived impurities in the elution pool.
Storage and Stability
Store at 4 to 30 °C (20% Ethanol)
Analysis Note
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
Legal Information
Sepharose is a trademark of Cytiva
- UPC:
- 23151804
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- GE17-1287-01