Anx Sepharose(R) Fast Flow High Sub

General description

ANX Sepharose^™ 4 Fast FLow (high sub) is a weak anion exchanger, with a different selectivity compared with traditional ion exchangers. It is optimized for the separation of larger proteins.

Application

ANX Sepharose^™ Fast FLow (high sub) is part of the Sepharose^™ Fast FLow ion exchange platform, which has been the industrial standard for ion exchange chromatography during recent decades. ANX Sepharose^™ 4 Fast FLow (high sub) is a weak anion exchanger medium with tertiary amine groups attached to the base matrix Sepharose^™ 4 Fast FLow via ether linkage and a hydrophilic spacer arm. The diethylaminopropylgroup is coupled in a mode that precludes formation of quaternary groups, which are typically seen on traditional DEAE media, resulting in a truly weak anion exchanger. The base matrix, Sepharose^™ 4 Fast Flow, is a highly cross-linked, 4% Agarose derivative with high chemical and physical stability and broad separation range. ANX Sepharose^™ 4 Fast FLow (high sub) has high chemical stability, allowing well proven cleaning-in-place (CIP) and sanitization protocols.

As member of the BioProcess media range, ANX Sepharose^™ 4 Fast FLow (high sub) meets industrial demands with security of supply and comprehensive technical and regulatory support.

Features and Benefits

• Weak anion exchanger with different selectivity compared with traditional ion exchangers.
• Applicable for separation of high molecular weight Proteins
• Developed in co-operation with leading large-scale pharmaceutical manufacturers
• High chemical stability allows for well proven CIP and sanitization protocols
• The hydrophilic nature of the base matrix ensures Low levels of non-specific binding leading to Low levels of host cell-derived impurities in the elution pool.

Storage and Stability

Store at 4 to 30 °C (20% Ethanol)

Analysis Note

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Legal Information

Sepharose is a trademark of Cytiva