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apamin (c15-1225-237)

Apamin (C15-1225-237)

Catalog No.
C15-1225-237
Manufacturer No.
A9459-.5MG
Manufacturer Name
Sigma-Aldrich
Quantity
0.5
Unit of Measure
MG
Price: $685.71
List Price: $761.90

Amino Acid Sequence Cys-Asn-Cys-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys-Ala-Arg-Arg-Cys-Gln-Gln-His-NH2 [Disulfide Bridges: 1-11, 3-15] General description Apamin, a bee venom is a polypeptide, that is made of 18 amino acids with two disulfide bridges.

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Amino Acid Sequence

Cys-Asn-Cys-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys-Ala-Arg-Arg-Cys-Gln-Gln-His-NH2 [Disulfide Bridges: 1-11, 3-15]

General description

Apamin, a bee venom is a polypeptide, that is made of 18 amino acids with two disulfide bridges.

Application

Apamin has been used in microbiological assays for the determination of antimicrobial activity of synthetic apamin and as a standard for MALDI (matrix-assisted laser desorption/ionization matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) and electrospray ionisation mass spectrometry (ESI-MS) analysis.

Biochem/physiol Actions

Apamin is a neurotoxin which can pass the blood-brain barrier. In human, it might cause peripheral nerve dysfunction, mainly seen after bee stings.

The only polypeptide neurotoxin that is known to pass the blood-brain barrier. Blocks ATP-type Ca+2-activated K+ channels.

Other Notes

Lyophilized from 0.1% TFA in H2O

UPC:
51385903
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
A9459-.5MG


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