Transferrin, majorly synthesized in the liver, is an abundant glycoprotein in the serum. The members of the transferrin superfamily have similar polypeptide folding patterns. Transferrin contains N- and C-terminal iron-binding homologous domains. Each of these domains is split into two subdomains having binding sites for iron and anions within the inter-subdomain cleft. The binding cleft opens and closes with iron releasing and iron binding. apo-Transferrin is an iron-free protein that arises after transferrin dissociates from its receptor. This product can be supplemented with iron or used to bind free iron present in media.Application:apo-Transferrin human has been used:to culture human primary pancreatic endothelial cells, Het1As (non-tumorous esophagus cells), and immortalized human colonic epithelial cells (HCEC-1CT)to culture α mouse liver 12 (AML-12) (mature hepatocytes) cellsas a source for human apo-transferrin for purification before crystallography
Specification: BioReagent, for cell culture, ≥98%(agarose gel electrophoresis), powder
MDL Number: MFCD00130536
Molecular Formula: C16H22N6O4
Molecular Weight: 362.38
PubChem CID: 638678
Isomeric SMILES: C1C[C@H](N(C1)C(=O)[C@H](CC2=CN=CN2)NC(=O)[C@@H]3CCC(=O)N3)C(=O)N
- UPC:
- 51131522
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 0.07 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A754970-100mg
- CAS:
- 11096-37-0
- Product Size:
- 100mg
- Hazard Statement Codes:
- H332
