Analytical, ~6000 KIU/mg, Off-White Powder Aprotinin is a serine protease inhibitor which is reactive against trypsin, chymotrypsin, plasmatic and glandular kininogenases, plasmin, kallkrein, urokinase, clotting factor XIIa, protein C, proteinases of the complement system, and leukocyte and tissue proteinases. It does not inhibit thrombin. Works by blocking the active sites of enzymes. Binding is reversible with most aprotinin-protease complexes dissociating at pH > 10 or < 3. Small amounts of aprotinin can be added to tubes of drawn blood to enable laboratory measurement of rapidly degraded proteins such as glucagon. Aprotinin can be labelled with fluorescein isothiocyanate. The conjugate retains its antiproteolytic and carbohydrate-binding properties and has been used as a fluorescent histochemical reagent for staining glycoconjugates (mucosubstances) that are rich in uronic or sialic acids. In cell biology aprotinin is used as an enzyme inhibitor to prevent protein degradation during lysis or homogenization of cells and tissues. Synonyms : Pancreatic Basic Trypsin Inhibitor polypeptide, Antagosan, Antikrein, Trasylol, Zymofren, Antagosan, Anikrein, Antilysin(e), BPTI, Bayer A 128, Kallikrein-trypsin inactivator, Fosten, Iniprol, Kunitz protease inhibitor, Onquinin, Repulson, RP-9921, Ryker 52G, Triazinin, Zymofren
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- UPC:
- 41141946
- Condition:
- New
- Availability:
- 3 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 0219038250
- Model Number:
- C831X95
- Temperature Control Device:
- Yes
