ARL 67156 trisodium salt

ARL 67156 trisodium salt is a newly synthesized analog of ATP which functions as a selective CD39 (ecto-ATPase) inhibitor. In addition, studies suggest that ARL 67156 trisodium salt also acts as a weak antagonist for the purinoceptors P2X and P2T and as an agonist for P2u. A common problem observed in the pharamacological classification of receptors is the susceptibility of antagonists and agonists to enzymatic degradation by the assay tissue used, which ARL 67156 trisodium salt may possibly resolve. It has been reported that ARL 67156 trisodium salt also potentiates the effects of UTP, ATP-γ-S, and ATP on purinoceptors via inhibiting dephosphorylation. Furthermore, ARL 67156 trisodium salt can be used as a probe to determine the action of nucleotides and in the classification of purinoceptors. ARL 67156 trisodium salt has a pIC50 = 4.62 and 5.1 in human blood and rat vas deferens, respectively. Specification: ≥98% Molecular Formula: C15H24Br2N5O12P3 Molecular Weight: 719.11 PubChem CID: 10078572 Isomeric SMILES: CCN(CC)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(C(P(=O)(O)O)(Br)Br)O)O)O Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/A335957-SCI_d4a47dad9e2af891cbcebc4c7503c557.pdf