General description
ARL 67156, a nucleotide/ATP analog is a competitive inhibitor of CD39. This ecto-ATPase inhibitor is presumed to be metabolically stable in biological studies due to its β, γ-dibromomethylene bridge.
Application
ARL 67156 trisodium salt hydrate has been used:
- to prevent ATP degradation during cerebrospinal fluid extraction
- as an ATPase inhibitor in ATP quantification assay for preventing ATP degradation in cytoplasm and mitochondrion
- as an ecto-ATPase inhibitor to treat cancer cells for ATP release assay
Biochem/physiol Actions
ecto-ATPase inhibitor; prevents metabolism of P2 purinoceptor agonists.
- UPC:
- 51413212
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A265-25MG