Amino Acid Sequence
Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr [Disulfide bridge: 7-23]
Application
Atrial Natriuretic Peptide rat has been used:
- In the absorption test to confirm the specificity of the anti-NP antibodies.
- To study the effects of atrial natriuretic peptide (ANP) on renal water and sodium regulation in rats.
- To study the integrated biological effects of ANP on myocardial infarction using mice models.
Biochem/physiol Actions
ANP production is regulated by factors associated with developmental, hormonal and hemodynamic processes. Its secretion is stimulated by atrial wall stretch, and ischemia.
Atrial natriuretic peptide (ANP) is synthesized in myoendocrine cells of the heart from which it is released into the circulation. It exerts natriuretic, diuretic, and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure homeostasis.
Other Notes
Lyophilized from 0.1% TFA in H2O
- UPC:
- 51152001
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A8208-.5MG
