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atuliflapon

Atuliflapon

Catalog No.
C007B-326391
Mfr. No.
A656323-1ml
Mfr. Name
Aladdin Scientific
Qty/UOM
1
UOM
EA
Price: $413.48
List Price: $459.42

Atuliflapon (AZD5718) is an orally active inhibitor of FLAP (5‑Lipoxygenase activating protein) , with an IC 50 of 2 nM. Atuliflapon is used in the study for coronary artery diseaseIn VitroAtuliflapon demonstrates a dose dependent and greater than

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Atuliflapon (AZD5718) is an orally active inhibitor of FLAP (5‑Lipoxygenase activating protein) , with an IC 50 of 2 nM. Atuliflapon is used in the study for coronary artery diseaseIn VitroAtuliflapon demonstrates a dose dependent and greater than 90% suppression of leukotriene production over 24 h. Atuliflapon exhibits an IC 50 of 39 nM for LTB 4. MCE has not independently confirmed the accuracy of these methods. They are for reference only.In VivoAtuliflapon exhibits t1/2 of 0.45 h and 2.1 h in rat and dog by iv injection, respectively . Atuliflapon shows no inhibition of 5-LO pathway activity in rodent blood . MCE has not independently confirmed the accuracy of these methods. They are for reference only.IC50& Target:IC50: 2 nM (FLAP). Specification: 10mM in DMSO Molecular Formula: C24H26N6O3 Molecular Weight: 446.5
UPC:
51321712
Condition:
New
Availability:
8-12 weeks
Weight:
1.06 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
A656323-1ml
CAS:
2041075-86-7
Product Size:
1ml

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