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bactenecin

Bactenecin

Catalog No.
C15-1342-810
Manufacturer No.
B2809-500UG
Manufacturer Name
Sigma-Aldrich
Quantity
500
Unit of Measure
UG
Price: $1,080.00
List Price: $1,200.00

Amino Acid Sequence Arg-Leu-Cys-Arg-Ile-Val-Val-Ile-Arg-Val-Cys-Arg-OH (Disulfide bridge: 3-11) General description Chemical structure: peptide Application Bactenecin′s activity has been studied as a cyclic molecule as well as in a linear

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Amino Acid Sequence

Arg-Leu-Cys-Arg-Ile-Val-Val-Ile-Arg-Val-Cys-Arg-OH (Disulfide bridge: 3-11)

General description

Chemical structure: peptide

Application

Bactenecin′s activity has been studied as a cyclic molecule as well as in a linear form. It was used to study the functional role of Trk1p in the mechanism of other antifungal peptides. It has been used to study chemokine and cytokine production, alteration of gene expression in host cells, and inhibition of proinflammatory responses of host cells to bacterial components.

Biochem/physiol Actions

Bactenecin is a 12-amino acid cationic antimicrobial peptide from bovine neutrophils. It strongly binds to LPS and perturbs the structure, fluidity and permeability of the inner membrane. This results in the leakage of cytosol and subsequent death of the bacteria.

Other Notes

Peptide antibiotic, originally isolated from bovine neutrophil granules

Keep container tightly closed in a dry and well-ventilated place.

UPC:
51111733
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
B2809-500UG


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