InformationBaricitinib phosphate (INCB-028050, LY-3009104) is a selectiveJAK1andJAK2inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Baricitinib is found to reduce or interrupt the passage of the virus into target cells and is used in the treatment research for COVID-19.TargetsJAK2 (Cell-free assay); JAK1 (Cell-free assay); TYK2 (Cell-free assay); JAK3 (Cell-free assay) 5.7 nM; 5.9 nM; 53 nM; >400 nM. Specification: 0.98 Molecular Formula: C16H20N7O6PS Molecular Weight: 469.41 PubChem CID: 44231848 Isomeric SMILES: CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/B413326-SCI_9d01bff38faadc1acf575d65bac2856f.pdf
- UPC:
- 12352106
- Condition:
- New
- Availability:
- 2 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- B413326-5mg
- CAS:
- 1187595-84-1
- Product Size:
- 5mg
