BAY-390 (C005B-309210)

Catalog No.: C005B-309210
Mfr. No.: SML3306-5MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: MG

Price: $293.35

List Price: $325.95

Biochem/physiol Actions BAY-390 is an orally active, potent and selective TRPA1 inhibitor (cellular Ca++ influx IC50 in nM by FLIPR = 16/hu, 19/monkey, 63/rat, 68/guinea pig, 73/mu, 81/dog: IC50 = 5.6 µ:M/hTRPC5, >:25 µ:M/human TRPV1/4,

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Description
Specifications

Biochem/physiol Actions

BAY-390 is an orally active, potent and selective TRPA1 inhibitor (cellular Ca++ influx IC50 in nM by FLIPR = 16/hu, 19/monkey, 63/rat, 68/guinea pig, 73/mu, 81/dog; IC50 = 5.6 µM/hTRPC5, >25 µM/human TRPV1/4, TRPC3/6, KCNK9 (TASK-3), CACNA1H (Cav3.2)) that shows in vivo efficacy in animal models of inflammatory pain (30 or 90 mg/kg mice, p.o.) and neurogenic pain (30 or 90 mg/kg rats, b.i.d. p.o.).

UPC:: 51171615
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML3306-5MG
CAS:: 2741956-55-6

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