BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D ( IC 50 =96 nM) and C1s ( IC 50 =1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin.In VitroBCX 1470 methanesulfonate is serine protease inhibitor. BCX 1470 methanesulfonate blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro, also blocked development of RPA-induced edema in the rat. MCE has not independently confirmed the accuracy of these methods. They are for reference only.IC50& Target:IC50: 96 nM (Factor D),1.6 nM (C1s),326 nM (Trypsin). Specifications and Purity: 10mM in DMSO. Molecular Formula: C15H14N2O5S3. Molecular Weight: 398.48.
- UPC:
- 12352005
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- B654896-1ml
- CAS:
- 217099-44-0
- Product Size:
- 1ml
