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beta-Amanitin from Amanita phalloides

Catalog No.
C15-1223-130
Manufacturer No.
A1304-1MG
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
MG
Price: $1,482.86
List Price: $1,647.62

β-Amanitin belongs to the family of amatoxins. Amanitins are made of bicyclic octapeptides.

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General description

β-Amanitin belongs to the family of amatoxins. Amanitins are made of bicyclic octapeptides. β-Amanitin is composed of a carboxyl group and is acidic in nature.

Application

β-Amanitin from Amanita phalloides has been used:

  • as a calibration standard for the quantification of β-Amanitin using liquid chromatography-high resolution-mass spectrometry/mass spectrometry (LC-HR-MS/MS) method.
  • to determine its concentration in urine samples by capillary zone electrophoresis (CZE).
  • in the analysis of β-amanitin in toxic mushrooms by liquid chromatography coupled to time-of-flight mass spectrometry.

Biochem/physiol Actions

Toxic constituent of the mushroom, Amanita phalloides, inhibits eukaryotic RNA polymerase II and III, but not RNA polymerase I or bacterial RNA polymerase. Inhibits mammalian protein synthesis.

UPC:
51451901
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
A1304-1MG


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