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B-LACTOGLOBULIN FROM BOVINE MILK (C15-1291-712)

Catalog No.
C15-1291-712
Mfr. No.
L2506-1G
Mfr. Name
Sigma-Aldrich
Qty/UOM
1
UOM
GR
Price: $389.75
List Price: $433.05

β-Lactoglobulin plays a key role in immune response and modulates IgM levels and cell proliferation. β-Lactoglobulin from bovine is a model system for protein folding studies and denaturation kinetics.

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General description

β-Lactoglobulin plays a key role in immune response and modulates IgM levels and cell proliferation. β-Lactoglobulin from bovine is a model system for protein folding studies and denaturation kinetics. Polymorphisms in the β-lactoglobulin modulates bovine milk production and composition.

A member of the lipocalin family, βLg is a small protein of 162 amino acids with a molecular mass of ∼18,400 Da,. It has an eight-stranded β-barrel (strands A-H) succeeded by a three-turn a-helix and a final β-strand (strand I) that forms part of the dimerization interface.

Milk from dairy cows contains the protein β-lactoglobulin (BLG). It naturally occurs in a number of genetic variants, and the most prevalent bovine variants are BLG A and BLG B.

Application

β-Lactoglobulin from bovine milk has been used:

  • for the generation of calibration curve for protein solubility index
  • in acid-base titration
  • as a standard for surface hydrophobicity analysis

β-Lactoglobulin was used in a cytologic assay for diagnosis of food hypersensitivity in patients with irritable bowel syndrome.

Quality

Contains β-lactoglobulins A and B which can be isolated chromatographically.

UPC:
51201651
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
L2506-1G
CAS:
9045-23-2

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