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[beta-mercapto-beta,beta-cyclopentamethylenepropionyl1, o-et-tyr2, val4, arg8]-vasopressin

(B-MERCAPTO-B B-CYCLOPENTAMETHYLENE- PROPIONYL1 O-ET-TYR2 VAL4 ARG8)- VASOPRESSIN

Catalog No.
C15-1694-701
Mfr. No.
V4253-1MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
1
UOM
MG
Price: $856.96
List Price: $952.18

Amino Acid Sequence (1-Mercaptocyclohexyl)acetyl-Tyr(O-Ethyl)-Phe-Val-Asn-Cys-Pro-Arg-Gly-NH2 [Disulfide Bridge: 1-6] Application [Beta-Mercapto-beta, beta-cyclopentamethylenepropionyl 1 , O-Et-Tyr 2 , Val 4 , Arg 8 ]-Vasopressin is a potent V1a

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Amino Acid Sequence

(1-Mercaptocyclohexyl)acetyl-Tyr(O-Ethyl)-Phe-Val-Asn-Cys-Pro-Arg-Gly-NH2 [Disulfide Bridge: 1-6]

Application

[Beta-Mercapto-beta, beta-cyclopentamethylenepropionyl1, O-Et-Tyr2, Val4, Arg8]-Vasopressin is a potent V1a and V2 vasopressin receptor anatgonist, used for examining the impact of vasopressin V1receptor blockade in rats.The product was also be used for visualizing cell surface V1a receptors in rat hepatocytes by using high-affinity fluorescent linear antagonist, Rhm8 -PVA.

Biochem/physiol Actions

Vasopressin also known as antidiuretic hormone (ADH) or argipressin can stimulate three acid-base transporters and hence increases the capability of the cell to regulate pHi.ADH can induce reversible translocation of aquaporin-CD water channels from intracellular vesicles to apical plasma membrane, which in turn increases the water permeability of collecting duct cells.

UPC:
51263169
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
V4253-1MG
CAS:
77453-01-1

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