Application
β-NADPH is suitable for use in:
- desaturation of fatty acids
- an assay of desaturase activity
- the histochemical detection of NADPH diaphorase activity in rat, rabbit and pheasant thoracic spinal cord
- the measurement of glutathione in oligodendrocyte cultures
Biochem/physiol Actions
β-NADPH is the reduced form of NADP+ generated by the pentose phosphate pathway. It serves as a carrier of reducing power and transfers H+ and 2 e– to the oxidized precursors in the reduction reactions of biosynthesis. It is an essential coenzyme for the catalytic activity of enzymes such as glutathione reductase, diacetyl reductase, dihydrofolate reductase, glutamic dehydrogenase, p-hydroxybenzoate hydroxylase, NADPH-FMN oxidoreductase, nitrate reductase, and thioredoxin reductase. It is also a part of cytochrome P450 electron transport systems.
NADPH is an electron donor and a cofactor for many redox enzymes including nitric oxide synthetase.
Preparation Note
Chemically reduced.
Other Notes
Packaged based on solid weight.
- UPC:
- 41141625
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- N1630-5G
- CAS:
- 2646-71-1
