General description
Biliverdin (BV) is considered as a near-infrared (NIR)-absorbing pigment, that is endogenic. It is a linear tetrapyrrolic intermediate of heme degradation (heme catabolism) to bilirubin. The bile of amphibia and birds contains only biliverdine, no bilirubin.
Application
Biliverdin hydrochloride has been used:
- as a treatment to J774A.1 cells to study its role in alternation of beta (β)-endorphins level
- as a commercial standard for the detection of biliverdin in mouse unstable and stable plaques tissues using liquid chromatography-tandem mass spectrometry (LC-MS-MS)
- to add to Fucci-containing cells to improve the mIFP signal
- to examine its impact on infrared fluorescent protein (iRFP) in some retinal preparations
Biochem/physiol Actions
Biliverdin (BV) is an excellent anti-inflammatory agent that protects against lipopolysaccharides (LPS)-induced lung injury in mouse endothelial cells. It aids protection in polymicrobial sepsis. Biliverdin has cytoprotective effects on rat livers and protects from prolonged ischemia and reperfusion injury. It also shows antioxidant activities.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Molecular Weight: 619.11. Empirical Formula: C33H34N4O6 · HCl. Quality Level: 100. Assay: ≥. 97.0% (TLC). form: powder or crystals. application(s): metabolomicsvitamins, nutraceuticals, and natural products. storage temp.: −. 20°C. SMILES string: Cl.CC1: C(C: C)C(\NC1: O): C\c2[nH]c(/C: C3\N: C(\C: C4/NC(: O)C(C: C): C4C)C(C): C3CCC(O): O)c(CCC(O): O)c2C. InChI: 1S/C33H34N4O6.ClH/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26. /h7-8,13-15,35H,1-2,9-12H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41). 1H/b26-13-,27-14-,28-15-. . InChI key: KTRFJVRKVQROKS-UJCZHUFNSA-N. Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H315 - H319 - H335. Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.
- UPC:
- 51131746
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 30891-50MG