BIMU8 hydrate

Catalog No.: C15-1212-497
Manufacturer No.: B4063-5MG
Manufacturer Name: Sigma-Aldrich
Quantity: 5
Unit of Measure: MG

Price: $442.65

List Price: $491.84

Biochem/physiol Actions BIMU8 hydrate is a potent 5-HT 4 serotonin receptor agonist. Serotonin (5-HT) is a major neurotransmitter that acts through a family of GPCRs and one ion channel.

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Biochem/physiol Actions

BIMU8 hydrate is a potent 5-HT₄ serotonin receptor agonist. Serotonin (5-HT) is a major neurotransmitter that acts through a family of GPCRs and one ion channel. 5-HT₄ receptor is GPCR expressed in many tissues, including brain, and modulates dopamine secretion, learning, and memory. BIMU8 is a full agonist at 5-HT₄, but it binds differently than the endogenous ligand, 5-HT, shown through site-directed mutagenesis studies. It depolarizes neurons and was used to localize 5-HT₄ to somatic but not dendritic regions of CA1 pyramidal neurons.

UPC:: 51361501
Condition:: New
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: B4063-5MG

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