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553525-25MG
Sigma-Aldrich
RAD51 Inhibitor, B02 - CAS 1290541-46-6 - Calbiochem
Price: $315.92List Price: $351.02A cell-permeable pyridinylvinyl-quinazolinone compound that is shown to specifically inhibit human RAD51 (IC 50 = 27.4 µM). -
613-4630
Rb Anti-Sh IgG F(ab')2 Biotin MX 500æg
Price: $455.63List Price: $506.25This product has been assayed against 1.0 ug of Sheep IgG in a standard capture ELISA using Peroxidase Conjugated Streptavidin #S000-03 and ABTS (2,2’-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid]) code # ABTS-100 as a substrate for 30 minutes at -
613-4603
Rb Anti-Sh IgG F(c) Biotin 1.5mg
Price: $329.71List Price: $366.34This product has been assayed against 1.0 ug of Sheep IgG in a standard capture ELISA using Peroxidase Conjugated Streptavidin #S000-03 and ABTS (2,2’-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid]) code # ABTS-100 as a substrate for 30 minutes at -
555460-25MG-MA cell-permeable (quinoxalinylmethylidene-D-Tryptophanyl)hydrazide that directly targets Rho GEF binding domain (Kd = 354 nM for RhoA), thereby prevents Rho from interacting with its GEFs (including LARG, DBL, LBC, p115 RhoGEF, and PDZ RhoGEF), but
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566332-10MG
Sigma-Aldrich
Sirt1 Inhibitor VII, Inauhzin - Calbiochem (C15-1305-836)
Price: $369.18List Price: $410.20A cell-permeable phenothiazine derivative that selectively inhibits SirT1 (IC 50 𕟪.0 µM), but not SirT2, SirT3, or HCAC8 (IC 50 >50 µM), activity and effectively elevates cellular p53 lysine acetylation (Effective conc. -
573127-5MG
Sigma-Aldrich
STAT3 Inhibitor XII, SPI - Calbiochem (C15-1306-182)
Price: $668.57List Price: $742.86A cell-permeable STAT3 SH2 domain-derived (588-615) 28-mer peptide that competitively prevents STAT3 binding to cognate pTyr peptide motif, represses STAT3 dimerization, induces apoptosis and acts as a selective constitutive STAT3 activation -
573128-10MG
Sigma-Aldrich
STAT3 Inhibitor XIII, C188-9 - Calbiochem (C15-1306-183)
Price: $315.92List Price: $351.02A cell-permeable binaphthol-sulfonamide that competes against pY proteins for Stat3 SH2 domain binding. Shown to inhibit G-CSF-induced (100 ng/ml for 15 min following 1 h drug pretreatment) Stat3 tyr705 phosphorylation in 6 human AML cell lines (IC -
407625-5MGA cell-permeable, arylsulphonamidyl thiophene amide that is shown to reduce IL-6-induced STAT3 transcriptional activity (EC 50 = 15 µM) in a luciferase reporter assay, in HeLa cells. It selectively inhibits STAT3, but not STAT1,
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5051560001A cell-permeable trihydroxyflavone compound that inhibits androgen receptor peptide, IκBα, and Topoisomerase I SUMOylation in cell-free assays (>90% at 30 µM) by selectively preventing the transfer of SUMO (Cat. Nos.
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5049070001A cell-permeable, triazolyl-vinyl-oxadiazole compound that targets adenosine site of the NAD + pocket in the TNKS PARP domain and acts as a potent and highly selective tankyrase inhibitor (IC 50 = 33 and 26 nM, respectively, against
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1106640500Analysis Note Appearance (clearness): clear Appearance (colour): yellowish-brown pH-value (25 °C): 7.9 - 8.
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648492-50MG
Sigma-Aldrich
TRPM4 inhibitor, 9-Phenanthrol - CAS 484-17-3 - Calbiochem
Price: $207.21List Price: $230.24A cell permeable hydroxytricyclic derivative that acts as a specific and reversible inhibitor of transient receptor potential melastatin 4 (TRPM4) (IC 50 = 20 µM in HEK293 cells). Does not affect TRPM5 and cystic fibrosis transmembrane