Radiolabeled Receptor Ligands

(-)-Securinine is plant-derived alkaloid and also a GABAA receptor antagonist.

(-)-Securinine is plant-derived alkaloid and also a GABAA receptor antagonist.

(1E)-4-HYDROXY-3 4-DIPHENYL-2-CYCLOPENTEN-1-ONE SEMICARBAZONE-

(1R,2R)-(+)-1,2-Bis(4-dimethylaminophenyl)ethylenediamine tetrahydrochloride.

(1R,2R)-(+)-1,2-Bis(4-dimethylaminophenyl)ethylenediamine tetrahydrochloride.

(1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and acts as a potent GPR88 receptor agonist, with an EC 50 of 3 nM in cell-free assay, and 603 nM in cell assay.In Vitro(1R,2R)-2-PCCA (Example 3) is a potent GPR88 receptor agonist, with an

(1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and acts as a potent GPR88 receptor agonist, with an EC 50 of 3 nM in cell-free assay, and 603 nM in cell assay.In Vitro(1R,2R)-2-PCCA (Example 3) is a potent GPR88 receptor agonist, with an

(1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and acts as a potent GPR88 receptor agonist, with an EC 50 of 3 nM in cell-free assay, and 603 nM in cell assay.In Vitro(1R,2R)-2-PCCA (Example 3) is a potent GPR88 receptor agonist, with an

(1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and acts as a potent GPR88 receptor agonist, with an EC 50 of 3 nM in cell-free assay, and 603 nM in cell assay.In Vitro(1R,2R)-2-PCCA (Example 3) is a potent GPR88 receptor agonist, with an

(1R,2R)-N,N-Bis{2-[bis(3,5-dimethylphenyl)phosphino]benzyl}cyclohexane-1,2-diamine.

(8R,9S)-Talazoparib ((8R,9S)-BMN-673) is an enantiomer of Talazoparib. (8R,9S)-Talazoparib is an PARP1 inhibitor, with an IC 50 of 144 nMIn Vitro(8R,9S)-Talazoparib shows an EC 50 of 864 nM in cellular PARylation assay. (8R,9S)-Talazoparib shows an

(8R,9S)-Talazoparib ((8R,9S)-BMN-673) is an enantiomer of Talazoparib. (8R,9S)-Talazoparib is an PARP1 inhibitor, with an IC 50 of 144 nMIn Vitro(8R,9S)-Talazoparib shows an EC 50 of 864 nM in cellular PARylation assay. (8R,9S)-Talazoparib shows an