Radiolabeled Receptor Modulators

Benztropine is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM.An antagonist of the mAChR.

Benztropine is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM.An antagonist of the mAChR.

Benztropine is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM.An antagonist of the mAChR.

BIO-32546 (example 12b, S-isomer) is an autotaxin (ATX) modulator (IC 50 : 1 nM), extracted from the patent US20170158687A1Form:SolidIC50&amp: Target:Autotaxin.

BIO-32546 (example 12b, S-isomer) is an autotaxin (ATX) modulator (IC 50 : 1 nM), extracted from the patent US20170158687A1Form:SolidIC50&amp: Target:Autotaxin.

InformationBML-190 (IMMA) is a selectivecannabinoid CB2 receptorinverse agonist withKiof 435 nM, with 50-fold selectivity over CB1 receptor.In vitroBML-190 has 50-fold selectivity for CB2 receptors over CB1 receptors. In HEK-293 cells stably

Biochem/physiol Actions Br-PBTC is a selective and potent type II positive allosteric modulator (PAM) that potentiates the opening of the nicotinic acetylcholine receptors (nAChR) subtypes containing &#945:4&#946:2, &#945:2&#946:2 and

Biochem/physiol Actions Br-PBTC is a selective and potent type II positive allosteric modulator (PAM) that potentiates the opening of the nicotinic acetylcholine receptors (nAChR) subtypes containing &#945:4&#946:2, &#945:2&#946:2 and

Biochem/physiol Actions BTD is a potent and selective activator of the transient receptor potential canonical channel 5 (TRPC5). BTD can also activate heteromeric channels composed of TRPC5 and its closest relatives TRPC1 or TRPC4.

Biochem/physiol Actions BTD is a potent and selective activator of the transient receptor potential canonical channel 5 (TRPC5). BTD can also activate heteromeric channels composed of TRPC5 and its closest relatives TRPC1 or TRPC4.

A competitive antagonist of Capsaicin (Cat. No.

CARM1-IN-1 is a potent and specific CARM1(Coactivator-associated arginine methyltransferase 1) inhibitor with IC50 of 8.6 uM: shows very low activity against PRMT1 and SET7(IC50 &gt: 600 uM).IC50 value: 8.6 uM Target: CRAM1 inhibitorin vitro: