Leukotrienes

Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes, where the products of enzymatic origin, via Leukotriene A4 (LTA4) hydrolase, are stereospecifically 12(R). Non-enzymatic hydrolysis products are racemic

Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes, where the products of enzymatic origin, via Leukotriene A4 (LTA4) hydrolase, are stereospecifically 12(R). Non-enzymatic hydrolysis products are racemic

An isomer of LTB4 which would not be expected to occur in either non-enzymatic hydrolysis products, or in the enzymatic products of LTA4 hydrolase has significantly reduced activity compared to LTB4.

An isomer of LTB4 which would not be expected to occur in either non-enzymatic hydrolysis products, or in the enzymatic products of LTA4 hydrolase has significantly reduced activity compared to LTB4.

Leukotrienes comprise of a family of endogenous metabolites of certain fatty acids and are related to prostaglandins and thromboxanes. Generally derived from leukocytes and possess a conjugated triene structure. Leukotriene B4 is a chemotactic agent

Leukotrienes comprise of a family of endogenous metabolites of certain fatty acids and are related to prostaglandins and thromboxanes. Generally derived from leukocytes and possess a conjugated triene structure. Leukotriene B4 is a chemotactic agent

Phytochemical from cruciferous vegetables that demonstrates anticancer and chemopreventative effects (10-30 &microM) involving the induction of Phase 2 enzymes, promotion of apoptosis, induction of cell cycle arrest, inhibition of cell

Found in the lipid A part of LPS and useful as chemical marker of endotoxins accumulates during long-chain 3-hydroxy-acyl-CoA dehydrogenase and mitochondrial trifunctional protein deficiencies, inducing oxidative stress and leading to mitochondrial

4-METHOXY-1 3 5-CYCLOHEPTATRIENE-1-CARBOXYLIC ACID-

5(S),6(R)-Lipoxin A4-d5 (5(S),6(R)-LXA4-d5) contains five deuterium atoms at the 19, 19', 20, 20, and 20 positions. It is used as an internal standard for quantification of 5(S),6(R)-LXA4 by GC- or LC-mass spectrometry (MS). 5(S),6(R)-Lipoxin A4 is

5(S),6(R)-Lipoxin A4-d5 (5(S),6(R)-LXA4-d5) contains five deuterium atoms at the 19, 19', 20, 20, and 20 positions. It is used as an internal standard for quantification of 5(S),6(R)-LXA4 by GC- or LC-mass spectrometry (MS). 5(S),6(R)-Lipoxin A4 is

5(S)-HPETE is a monohydroperoxy polyunsaturated fatty acid produced by 5-lipoxygenase metabolism of arachidonic acid and a biosynthetic precursor to leukotrienes. 5(S)-HPETE is described to induce c-fos without inducing c-jun in TA1 cells,