Cross-linkers

DescriptionLigand for asymmetric Negishi cross-coupling of secondary allylic chlorides.

Application 2-(1-(1-( tert -Butoxycarbonyl)piperidin-3-yl)-1 H -pyrazol-4-yl)acetic acid is useful as a rigid linker in PROTAC development for targeted protein degradation as well as chemical conjugates. Incorporation of rigidity into the linker

DescriptionThis heterobifunctional, PEGylated crosslinker 2-(2-((7-(tert-butoxy)-7-oxoheptyl)oxy)ethoxy)acetic acid features a carboxyl group at one end and a t-butyl protected carboxylic acid at the other and exhibits both hydrophobic and

DescriptionThis heterobifunctional, PEGylated crosslinker 2-(2-(oct-7-yn-1-yloxy)ethoxy)acetic acid features a carboxyl group at one end and an alkyne at the other and exhibits both hydrophobic and hydrophilic moieties for use in biological

Application Lithium 2-(3-(4-( tert -Butoxycarbonyl)-1 4-diazepan-1-yl)pyrazin-2-yl)acetate is useful as a rigid linker in PROTAC development for targeted protein degradation as well as chemical conjugates. Incorporation of rigidity into the linker

Application Sulfonyl fluoride motif can be used as a connector for the assembly of -SO2- linked small molecules with proteins or nucleic acids. This new click chemistry approach through sulfates is a complimentary approach to using amides and

Application Sulfonyl fluoride motif can be used as a connector for the assembly of -SO 2 - linked small molecules with proteins or nucleic acids. This new click chemistry approach through sulfates is a complimentary approach to using amides and

2-Iminothiolane, Hydrochloride is a thiolating agent that is useful in cross-linking proteins.A thiolane derivitization agent.Application：2-Iminothiolane hydrochloride has been used in the synthesis of thiolated PEG (poly(ethylene glycol). It may be

2-Iminothiolane, Hydrochloride is a thiolating agent that is useful in cross-linking proteins.A thiolane derivitization agent.Application：2-Iminothiolane hydrochloride has been used in the synthesis of thiolated PEG (poly(ethylene glycol). It may be

2-Iminothiolane, Hydrochloride is a thiolating agent that is useful in cross-linking proteins.A thiolane derivitization agent.Application：2-Iminothiolane hydrochloride has been used in the synthesis of thiolated PEG (poly(ethylene glycol). It may be

2-Iminothiolane, Hydrochloride is a thiolating agent that is useful in cross-linking proteins.A thiolane derivitization agent.Application：2-Iminothiolane hydrochloride has been used in the synthesis of thiolated PEG (poly(ethylene glycol). It may be

2-Iminothiolane, Hydrochloride is a thiolating agent that is useful in cross-linking proteins.A thiolane derivitization agent.Application：2-Iminothiolane hydrochloride has been used in the synthesis of thiolated PEG (poly(ethylene glycol). It may be