Lipoxygenase Inhibitors

A potent, reversible, and selective inhibitor of ALDH1A1 (IC₅₀ = 40 nM for the human form).

A cell permeable inhibitor of necrosis that also demonstrates strong mitochondrial reactive oxygen species and ONOO- scavenging activity localizes in mitochondria, selectively blocking oxidative stress-induced necrotic cell death (0.1 &muM

Application:Nitisinone has been used:to induce liver injury,to treat Ixodes scapularis tick cells to inhibit the activity of hydroxyphenylpyruvate dioxygenase,in supplemented water to block the accumulation of toxic metabolites in human hepatocyte

Application:Nitisinone has been used:to induce liver injury,to treat Ixodes scapularis tick cells to inhibit the activity of hydroxyphenylpyruvate dioxygenase,in supplemented water to block the accumulation of toxic metabolites in human hepatocyte

Application Octyl-( R )-2 hydroxyglutarate (HG) has been used as a membrane permeamble oncometabolite in gliblostoma cells to test its effects on NANOG transcription factor expression. It has also been used as a competitive inhibitor of the

Application Octyl-( R )-2 hydroxyglutarate (HG) has been used as a membrane permeamble oncometabolite in gliblostoma cells to test its effects on NANOG transcription factor expression. It has also been used as a competitive inhibitor of the

PALDA is an endogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. PALDA is inactive at TRPV1 and CB1 receptors (at concentrations up to 5 μM) and does not inhibit AMT or FAAH (IC|50|&gt: 25 μM).

PALDA is an endogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. PALDA is inactive at TRPV1 and CB1 receptors (at concentrations up to 5 μM) and does not inhibit AMT or FAAH (IC|50|&gt: 25 μM).

A cell-permeable, adenosine-substituted, isoindolinone compound that acts as a potent inhibitor of PARP-1 (IC 50 = 45 nM). Shown to offer cytoprotective effects against oxidative damage in cells and in in vivo models of reperfusion injury and

General description Donor:hydrogen-peroxide oxidoreductase Peroxidase (POD) (E.C.

Horseradish peroxidase (HRP) is a vital and a widely studied heme-containing enzyme, isolated from a hardy perennial herb, horse radish. It catalyzes the oxidation of various organic and inorganic compounds by using hydrogen peroxide as substrates.

Horseradish peroxidase (HRP) is a vital and a widely studied heme-containing enzyme, isolated from a hardy perennial herb, horse radish. It catalyzes the oxidation of various organic and inorganic compounds by using hydrogen peroxide as substrates.