Lipoxygenase Inhibitors

InformationTP0463518 TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with Ki of 5.3 nM for human PHD2. TP0463518 inhibits human PHD1, human PHD3 and monkey PHD2 with IC50 of 18 nM, 63 nM and 22 nM,

InformationTP0463518 TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with Ki of 5.3 nM for human PHD2. TP0463518 inhibits human PHD1, human PHD3 and monkey PHD2 with IC50 of 18 nM, 63 nM and 22 nM,

InformationTP0463518 TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with Ki of 5.3 nM for human PHD2. TP0463518 inhibits human PHD1, human PHD3 and monkey PHD2 with IC50 of 18 nM, 63 nM and 22 nM,

Acts as an electron acceptor commonly used by cells. This is used in vitro to study NADP and how it accepts electrons, among other applications.An endogenous electron acceptor and the common form of NADPApplication：β-Nicotinamide adenine

Acts as an electron acceptor commonly used by cells. This is used in vitro to study NADP and how it accepts electrons, among other applications.An endogenous electron acceptor and the common form of NADPApplication：β-Nicotinamide adenine

Acts as an electron acceptor commonly used by cells. This is used in vitro to study NADP and how it accepts electrons, among other applications.An endogenous electron acceptor and the common form of NADPApplication：β-Nicotinamide adenine

Acts as an electron acceptor commonly used by cells. This is used in vitro to study NADP and how it accepts electrons, among other applications.An endogenous electron acceptor and the common form of NADPApplication：β-Nicotinamide adenine

Acts as an electron acceptor commonly used by cells. This is used in vitro to study NADP and how it accepts electrons, among other applications.An endogenous electron acceptor and the common form of NADPApplication：β-Nicotinamide adenine

Application VAS2870 has been used as a nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) inhibitor: to study the importance of NOX-derived reactive oxygen species in cytoskeletal organization, proper localization of E-cadherin

Application VAS2870 has been used as a nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) inhibitor: to study the importance of NOX-derived reactive oxygen species in cytoskeletal organization, proper localization of E-cadherin

Biochem/physiol Actions VH298 is a cell-permeable small molecule that disrupts the interaction of VHL with Hypoxia-inducible factor HIF-&#945:, stabilizing HIF-&#945: and inducing a hypoxic response. Hypoxia-inducible factors (HIFs) are

Biochem/physiol Actions VH298 is a cell-permeable small molecule that disrupts the interaction of VHL with Hypoxia-inducible factor HIF-&#945:, stabilizing HIF-&#945: and inducing a hypoxic response. Hypoxia-inducible factors (HIFs) are