Phospholipase Inhibitors

Biochem/physiol Actions ML211 is a very potent, dual inhbitor of lysophospholipase 1 (LYPLA1: IC 50 = 17 nM) and lysophospholipase 2 (LYPLA2: IC 50 = 30 nM).

Biochem/physiol Actions ML211 is a very potent, dual inhbitor of lysophospholipase 1 (LYPLA1: IC 50 = 17 nM) and lysophospholipase 2 (LYPLA2: IC 50 = 30 nM).

Application ML240 has been used as an inhibitor of D2 ATPase activity of valosin-containing protein. Biochem/physiol Actions ML240 is a selective, ATP-competetive inhibitor of AAA ATPase p97, also called valosine containing protein (VCP).

Application ML240 has been used as an inhibitor of D2 ATPase activity of valosin-containing protein. Biochem/physiol Actions ML240 is a selective, ATP-competetive inhibitor of AAA ATPase p97, also called valosine containing protein (VCP).

Biochem/physiol Actions ML298 is a potent, specific inhibitor of Phospholipase D2 (PLD2: IC 50 = 355 nM). ML298 does not affect PLD1 activity at concentrations up to 20 &#956:M.

Biochem/physiol Actions ML298 is a potent, specific inhibitor of Phospholipase D2 (PLD2: IC 50 = 355 nM). ML298 does not affect PLD1 activity at concentrations up to 20 &#956:M.

General description This gene encodes an apolipoprotein E receptor, a member of the low density lipoprotein receptor (LDLR) family. Apolipoprotein E is a small lipophilic plasma protein and a component of lipoproteins such as chylomicron remnants,

General description PIP5K3 belongs to a large family of lipid kinases that alter the phosphorylation status of intracellular phosphatidylinositol. Signaling by phosphorylated species of phosphatidylinositol regulates diverse cellular processes,

General description Phosphatidylcholine (PC)-specific phospholipases D (PLDs: EC 3.1.

MRS2279 diammonium is a selective and high affinity P2Y1 receptor antagonist, with a K i value of 2.5 nM and an IC 50 value of 51.6 nM. MRS2279 diammonium competitively inhibits ADP-promoted platelet aggregation with an pK b value of 8.05In

myo-Inositol hexasulfate hexapotassium salt possesses a molecular footprint and negative surface charge that is similar to that of phytic acid (InsP6), but with lower biological activity. The compound is used as a control in studies of the cellular

myo-Inositol hexasulfate hexapotassium salt possesses a molecular footprint and negative surface charge that is similar to that of phytic acid (InsP6), but with lower biological activity. The compound is used as a control in studies of the cellular