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P647574-5mg
PROTAC B-Raf degrader 1 (C007B-385605)
Price: $633.53List Price: $703.92PROTAC B-Raf degrader 1 (compound 2) is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf based on Cereblon ligand with anti-cancer activityIn VitroThe IC 50 values of PROTAC B-Raf degrader 1 (compound 2) towards MCF-7, -
P651713-100mg
PROTAC BET Degrader-10 (C007B-386617)
Price: $2,338.71List Price: $2,598.57PROTAC BET Degrader-10 is a potent BET protein BRD4 degrader extracted from patent WO2017007612A1, example 37, connected by ligands for Cereblon and BRD4 , with a DC 50 of 49 nM.Form:Solid. -
P651713-10mg
PROTAC BET Degrader-10 (C007B-386618)
Price: $584.88List Price: $649.86PROTAC BET Degrader-10 is a potent BET protein BRD4 degrader extracted from patent WO2017007612A1, example 37, connected by ligands for Cereblon and BRD4 , with a DC 50 of 49 nM.Form:Solid. -
P651713-25mg
PROTAC BET Degrader-10 (C007B-386619)
Price: $1,095.69List Price: $1,217.43PROTAC BET Degrader-10 is a potent BET protein BRD4 degrader extracted from patent WO2017007612A1, example 37, connected by ligands for Cereblon and BRD4 , with a DC 50 of 49 nM.Form:Solid. -
P651713-50mg
PROTAC BET Degrader-10 (C007B-386620)
Price: $1,642.99List Price: $1,825.54PROTAC BET Degrader-10 is a potent BET protein BRD4 degrader extracted from patent WO2017007612A1, example 37, connected by ligands for Cereblon and BRD4 , with a DC 50 of 49 nM.Form:Solid. -
P651713-5mg
PROTAC BET Degrader-10 (C007B-386621)
Price: $388.92List Price: $432.14PROTAC BET Degrader-10 is a potent BET protein BRD4 degrader extracted from patent WO2017007612A1, example 37, connected by ligands for Cereblon and BRD4 , with a DC 50 of 49 nM.Form:Solid. -
P649265-10mg
PROTAC BET degrader-2 (C007B-385993)
Price: $925.42List Price: $1,028.24PROTAC BET degrader-2 is a PROTAC connected by ligands for Cereblon and BET with an IC 50 value of 9.6 nM in cell growth inhibition in the RS4:11 cells and capable of achieving tumor regression.In VitroPROTAC BET degrader-2 (compound 25) is a highly -
P649265-5mg
PROTAC BET degrader-2 (C007B-385994)
Price: $584.88List Price: $649.86PROTAC BET degrader-2 is a PROTAC connected by ligands for Cereblon and BET with an IC 50 value of 9.6 nM in cell growth inhibition in the RS4:11 cells and capable of achieving tumor regression.In VitroPROTAC BET degrader-2 (compound 25) is a highly -
P659451-1mg
PROTAC BRD9-binding moiety 1 hydrochloride
Price: $259.17List Price: $287.97PROTAC BRD9-binding moiety 1 hydrochloride is a compound that binds to BRD9, and used for inhibiting BRD9 activity, based on PROTAC. -
P651375-10mg
PROTAC CBP/P300 Degrader-1 (C007B-386538)
Price: $1,929.62List Price: $2,144.03PROTAC CBP/P300 Degrader-1 is a potent PROTAC CBP/P300 degrader. PROTAC CBP/P300 Degrader-1 potently inhibited cell viability of multiple cancer cell linesIn VitroPROTAC CBP/P300 Degrader-1 shows LNCaP prostate cancer cell viability inhibition (IC -
P650778-25mg
PROTAC ERα Degrader-2 (C007B-386325)
Price: $2,981.57List Price: $3,312.86PROTAC ERα Degrader-2 comprises a IAP ligand binding group, a linker and an estrogen receptor α ( ERα ) binding group. PROTAC ERα Degrader-2 is an ERα degrader. Maximal ERα degradation at 30 μM concentration in human mammary tumor MCF7 cells. -
P650778-50mg
PROTAC ERα Degrader-2 (C007B-386326)
Price: $4,910.14List Price: $5,455.71PROTAC ERα Degrader-2 comprises a IAP ligand binding group, a linker and an estrogen receptor α ( ERα ) binding group. PROTAC ERα Degrader-2 is an ERα degrader. Maximal ERα degradation at 30 μM concentration in human mammary tumor MCF7 cells.