Protease Inhibitors

InformationCPD77 (MUN91789) is a potent inhibitor of SARS-​CoV-​2 main protease.

InformationCPD77 (MUN91789) is a potent inhibitor of SARS-​CoV-​2 main protease.

Application Protein degrader builiding block ( S , R , S )-AHPC-PEG 2 -butyl CO 2 H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology . This conjugate contains a von

Application Protein degrader builiding block ( S , R , S )-AHPC-PEG 6 -Azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology . This conjugate contains a von

Application Protein degrader builiding block ( S , R , S )-AHPC-PEG 6 -butyl azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology . This conjugate contains a von

Application Protein degrader building block ( S , R , S )-AHPC-pyridine-PEG 1 -piperazine hydrochloride enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology . This conjugate

Application Protein degrader building block ( S , R,S )-VL285 Phenol-piperazine-pyridine-alkyne-NH 2 hydrochloride enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology . This

A potent and reversible proteasome inhibitor, targeting the chymotryptic site on the 20S particle (Ki = 21 nM) reduces the degradation of ubiquitin-conjugated proteins in extracts blocks the degradation of long- and short-lived proteins in intact

A potent and reversible proteasome inhibitor, targeting the chymotryptic site on the 20S particle (Ki = 21 nM) reduces the degradation of ubiquitin-conjugated proteins in extracts blocks the degradation of long- and short-lived proteins in intact

(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology.Appearance:SolidIC50&amp: Target:VHLIn Vitro:PROTACs contain two

(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology.Appearance:SolidIC50&amp: Target:VHLIn Vitro:PROTACs contain two

(S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized E3 ligase ligand-linker conjugate , contains the VH032 VHL-based ligand and a linker to form PROTAC s. VH-032 is a selective and potent inhibitor of VHL/HIF-1α interaction with a K d of 185 nM,