Protease Inhibitors

A potent, selective, reversible, and competitive non-peptide inhibitor of cathepsin G (IC 50 = 53 nM and K i = 63 nM). Weakly inhibits chymotrypsin (K i = 1.

Cell-permeable cysteine protease inhibitor. Inhibits cathepsin B (k 2 /K i = 8.

A cell-permeable, symmetrical bis(acylamino)ketone compound that acts as a potent, selective, reversible inhibitor of cathepsin K (K i, = 22 nM). Also shown to inhibit cathepsin K in stably transfected CHO cells (IC 50 = 134 nM).

Amino Acid Sequence Arg-Lys-Leu-Leu-Trp-NH2 General description Cathepsin L Inhibitor is a histone H3-processing enzyme. It is important for maintaining epidermal homeostasis, regular hair follicle morphogenesis and cycling.

General description Human cathepsin V (GenBank Accession No. NM_001333.

Cathepsin X-IN-1 (compound 25) is a potent Cathepsin X inhibitor with an IC 50 of 7.13 µM. Cathepsin X-IN-1 decreases PC-3 cell migration with low cytotoxicForm:SolidIC50&amp: Target:IC 50 : 7.13 µM (Cathepsin X).

Cathepsin/Subtilisin Inhibitor inhibits members of the cysteine protease family including cathepsin L, and members of the serine protease family including subtilisin Carlsberg and thermitase. Cathepsin/Subtilisin Inhibitor is an inhibitor of

Cathepsin/Subtilisin Inhibitor inhibits members of the cysteine protease family including cathepsin L, and members of the serine protease family including subtilisin Carlsberg and thermitase. Cathepsin/Subtilisin Inhibitor is an inhibitor of

Cathepsin/Subtilisin Inhibitor inhibits members of the cysteine protease family including cathepsin L, and members of the serine protease family including subtilisin Carlsberg and thermitase. Cathepsin/Subtilisin Inhibitor is an inhibitor of

Cathepsin/Subtilisin Inhibitor inhibits members of the cysteine protease family including cathepsin L, and members of the serine protease family including subtilisin Carlsberg and thermitase. Cathepsin/Subtilisin Inhibitor is an inhibitor of

CC-90009 is a novel cereblon (CRBN) E3 ligase modulator and specifically targets GSPT1 (G1 to S phase transition 1) for proteasomal degradation.

CC-90009 is a novel cereblon (CRBN) E3 ligase modulator and specifically targets GSPT1 (G1 to S phase transition 1) for proteasomal degradation.