Protease Inhibitors

A reversible inhibitor of trypsin that binds to trypsin in a stoichiometric, pH-dependent manner (K d = 500 nM at pH 7.8).

Cysteine Protease inhibitor is an inhibitor of cysteine protease .IC50 &amp: Target: Cysteine Protease.

Tubulin polymerization inhibitor. Antitumorin vivo.

Tubulin polymerization inhibitor. Antitumorin vivo.

Biochem/physiol Actions dCBP-1 is a highly potent and selective bifunctional PROTAC degrader of CREB-binding protein (CBP) and p300 (p300/CBP) that potently inhibits enhancer-mediated transcription. dCBP-1 induces complete loss of p300/CBP in

Biochem/physiol Actions dCBP-1 is a highly potent and selective bifunctional PROTAC degrader of CREB-binding protein (CBP) and p300 (p300/CBP) that potently inhibits enhancer-mediated transcription. dCBP-1 induces complete loss of p300/CBP in

InformationDDD107498 DDD107498 (M-5717, DDD-498) is a P. falciparum translation elongation factor 2 inhibitor. DDD107498 exhibits a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite.

InformationDDD107498 DDD107498 (M-5717, DDD-498) is a P. falciparum translation elongation factor 2 inhibitor. DDD107498 exhibits a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite.

Biochem/physiol Actions Compound 11 (CP11) is an orally active and brain-penetrant delta-secretase (&#948:-secretase: AEP) inhibitor that selectively blocks AEP (IC50 = 710 nM) but not other related cysteine proteases (Caspase-3/-8 IC50 = 31.86/86.

Biochem/physiol Actions Compound 11 (CP11) is an orally active and brain-penetrant delta-secretase (&#948:-secretase: AEP) inhibitor that selectively blocks AEP (IC50 = 710 nM) but not other related cysteine proteases (Caspase-3/-8 IC50 = 31.86/86.

Desthiazolylmethyloxycarbonyl Ritonavir-d6 is a labeled metabolite of the selective HIV-1 protease inhibitor Ritonavir (sc-208310).Desthiazolylmethyloxycarbonyl Ritonavir-d6is a labeled metabolite of the selective HIV-1 protease inhibitor Ritonavir.

Desthiobiotin-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.Appearance:Viscous liquidIC50&amp: Target:PEGsIn Vitro:PROTACs contain two different ligands connected by a linker: one is a ligand for an E3 ubiquitin