Protease Inhibitors

FT206 is an inhibitor of carboxamides as ubiquitin-specific protrase extracted from patent WO 2020033707 A1, example 11-1Form:SolidIC50&amp: Target:Carboxamides as ubiquitin-specific protrase.

FT206 is an inhibitor of carboxamides as ubiquitin-specific protrase extracted from patent WO 2020033707 A1, example 11-1Form:SolidIC50&amp: Target:Carboxamides as ubiquitin-specific protrase.

InformationFulacimstat Fulacimstat (BAY1142524) is an orally available inhibitor of chymase with IC50 of 4 nM and 3 nM for human and hamster chymase enzyme, respectively.Targetshamster chymase enzyme (Cell-free assay): human chymase enzyme

A selective, irreversible, and cell-permeable competitive inhibitor of proprotein convertases, including furin/SPC1 (Ki = ~1 nM), SPC2/PC2 (Ki = 0.36 nM), SPC3/PC1/PC3 (Ki = 2.

A selective, irreversible, and cell-permeable competitive inhibitor of proprotein convertases, including furin/SPC1 (Ki = ~1 nM), SPC2/PC2 (Ki = 0.36 nM), SPC3/PC1/PC3 (Ki = 2.

Amino Acid Sequence Mpa-Mpa-Mpa-Mpa-Mpa-Mpa General description Furin is a calcium-dependent serine endoproteinase and belongs to the subtilisin-like proprotein/prohormone convertase (PC) family. It is distributed ubiquitously and has a

furin inhibitor peptide.

furin inhibitor peptide.

G3-C12 is a galectin-3 binding peptide, with K d of 88 nM, and shows anticancer activity.In VitroG3-C12 is a galectin-3 binding peptide, with high affinity (K d ) of 88 nM, but shows no affinity for other galectin family members or to other lectins.

G3-C12 is a galectin-3 binding peptide, with K d of 88 nM, and shows anticancer activity.In VitroG3-C12 is a galectin-3 binding peptide, with high affinity (K d ) of 88 nM, but shows no affinity for other galectin family members or to other lectins.

G3-C12 is a galectin-3 binding peptide, with K d of 88 nM, and shows anticancer activity.In VitroG3-C12 is a galectin-3 binding peptide, with high affinity (K d ) of 88 nM, but shows no affinity for other galectin family members or to other lectins.

Galectin-3 protein comprises a N-terminal flexible domain and a C-terminal carbohydrate-recognition domain (CRD). It is mapped to human chromosome 14q22.