Protease Inhibitors

InformationINCB054329 INCB054329 (INCB-054329, INCB-54329) is a structurally distinct bromodomain and extraterminal domain (BET) inhibitor with IC50 values of 44 nM, 5 nM, 9 nM, 1 nM, 28 nM, 3 nM, 119 nM and 63 nM for BRD2-BD1, BRD2-BD2, BRD3-BD1,

InformationINCB054329 INCB054329 (INCB-054329, INCB-54329) is a structurally distinct bromodomain and extraterminal domain (BET) inhibitor with IC50 values of 44 nM, 5 nM, 9 nM, 1 nM, 28 nM, 3 nM, 119 nM and 63 nM for BRD2-BD1, BRD2-BD2, BRD3-BD1,

InformationINCB054329 INCB054329 (INCB-054329, INCB-54329) is a structurally distinct bromodomain and extraterminal domain (BET) inhibitor with IC50 values of 44 nM, 5 nM, 9 nM, 1 nM, 28 nM, 3 nM, 119 nM and 63 nM for BRD2-BD1, BRD2-BD2, BRD3-BD1,

InformationINCB054329 INCB054329 (INCB-054329, INCB-54329) is a structurally distinct bromodomain and extraterminal domain (BET) inhibitor with IC50 values of 44 nM, 5 nM, 9 nM, 1 nM, 28 nM, 3 nM, 119 nM and 63 nM for BRD2-BD1, BRD2-BD2, BRD3-BD1,

1.Reactant in preparation of analogs of botulinum neurotoxin serotype A protease inhibitors. 2.Reactant in synthesis of stilbene-based antitumor agents. 3.Reactant in acid-catalyzed preparation of aromatic gem-dihalides from aldehydes and acid

1.Reactant in preparation of analogs of botulinum neurotoxin serotype A protease inhibitors. 2.Reactant in synthesis of stilbene-based antitumor agents. 3.Reactant in acid-catalyzed preparation of aromatic gem-dihalides from aldehydes and acid

1.Reactant in preparation of analogs of botulinum neurotoxin serotype A protease inhibitors. 2.Reactant in synthesis of stilbene-based antitumor agents. 3.Reactant in acid-catalyzed preparation of aromatic gem-dihalides from aldehydes and acid

1.Reactant in preparation of analogs of botulinum neurotoxin serotype A protease inhibitors. 2.Reactant in synthesis of stilbene-based antitumor agents. 3.Reactant in acid-catalyzed preparation of aromatic gem-dihalides from aldehydes and acid

1.Reactant in preparation of analogs of botulinum neurotoxin serotype A protease inhibitors. 2.Reactant in synthesis of stilbene-based antitumor agents. 3.Reactant in acid-catalyzed preparation of aromatic gem-dihalides from aldehydes and acid

A cell-permeable hydroxyethylene dipeptide isostere that acts as a highly specific and a potent inhibitor of &#947-secretase (A&#946 total IC 50 = 17 nM, A&#946 40 IC 50 = 48 nM, and A&#946 42 IC 50 = 67 nM in SHSY5Y cells overexpressing

A cell-permeable hydroxyethylene dipeptide isostere that acts as a highly specific and a potent inhibitor of &#947-secretase (A&#946 total IC 50 = 17 nM, A&#946 40 IC 50 = 48 nM, and A&#946 42 IC 50 = 67 nM in SHSY5Y cells overexpressing

Amino Acid Sequence Z-Leu-Leu-Leu-al General description Potent, reversible, and cell-permeable proteasome inhibitor (K i = 4 nM). Reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable stains of yeast by the 26S