Protease Inhibitors

J22352 is a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC 50 value of 4.7 nM. J22352 promotes HDAC6 degradation and induces anticancer effects by inhibiting autophagy and eliciting the antitumor immune

J22352 is a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC 50 value of 4.7 nM. J22352 promotes HDAC6 degradation and induces anticancer effects by inhibiting autophagy and eliciting the antitumor immune

JH-XI-10-02 is a PROTAC connected by ligands for Cereblon and CDK . JH-XI-10-02 is a highly potent and selective PROTAC CDK8 degrader, with an IC 50 of 159 nM. JH-XI-10-02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH-XI-10-02

JH-XI-10-02 is a PROTAC connected by ligands for Cereblon and CDK . JH-XI-10-02 is a highly potent and selective PROTAC CDK8 degrader, with an IC 50 of 159 nM. JH-XI-10-02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH-XI-10-02

JH-XI-10-02 is a PROTAC connected by ligands for Cereblon and CDK . JH-XI-10-02 is a highly potent and selective PROTAC CDK8 degrader, with an IC 50 of 159 nM. JH-XI-10-02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH-XI-10-02

JH-XI-10-02 is a PROTAC connected by ligands for Cereblon and CDK . JH-XI-10-02 is a highly potent and selective PROTAC CDK8 degrader, with an IC 50 of 159 nM. JH-XI-10-02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH-XI-10-02

JO146 is a Chlamydia trachomatis high temperature requirement A ( CtHtrA ) protease inhibitor with IC 50 s of 21.86 and 1.15 μM for CtHtrA and human neutrophil elastase (HNE), respectively. JO146 can be used to inhibits bacterial

JO146 is a Chlamydia trachomatis high temperature requirement A ( CtHtrA ) protease inhibitor with IC 50 s of 21.86 and 1.15 μM for CtHtrA and human neutrophil elastase (HNE), respectively. JO146 can be used to inhibits bacterial

Biochem/physiol Actions Kinesore is a cell penetrant and potent activator of kinesin-1 that induces kinesin light chain tetratricopeptide repeat domain-dependent kinesin-1 activation in the absence of organelle cargo-adaptor engagement. It

Biochem/physiol Actions Kinesore is a cell penetrant and potent activator of kinesin-1 that induces kinesin light chain tetratricopeptide repeat domain-dependent kinesin-1 activation in the absence of organelle cargo-adaptor engagement. It

Application Kininogen, low molecular weight from human plasma has been used to study rMASP-1 (recombinant mannose-binding lectin-associated serine protease 1)-mediated cleavage of LK (low molecular weight kininogen). It has been used as a standard

Extinction Coefficient: 0.7 High Molecular Weight kininogen, synthesized by hepatocytes, is a multifunctional protein.