Protease Inhibitors

Biochem/physiol Actions MF-094 is a potent inhibitor of ubiquitin specific protease 30 (USP30), a de-ubiquitinating enzymes (DUB) that opposes the action of parkin-mediated ubiquitination in clearing damaged mitochondria. MF-094 is selective for

Biochem/physiol Actions MF-094 is a potent inhibitor of ubiquitin specific protease 30 (USP30), a de-ubiquitinating enzymes (DUB) that opposes the action of parkin-mediated ubiquitination in clearing damaged mitochondria. MF-094 is selective for

Biochem/physiol Actions MF-095 is a control probe for MF-094, which is a potent inhibitor of ubiquitin specific protease 30 (USP30)

Biochem/physiol Actions MF-095 is a control probe for MF-094, which is a potent inhibitor of ubiquitin specific protease 30 (USP30)

Amino Acid Sequence Z-Leu-Leu-Leu-al General description Potent, reversible, and cell-permeable proteasome inhibitor (K i = 4 nM). Reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable stains of yeast by the 26S

MG-132 is an inhibitor of proteasome with IC50 of 100 nM, and also inhibits calpain with IC50 of 1.2 μM.A proteasome and NF-κB inhibitor.

MG-132 is an inhibitor of proteasome with IC50 of 100 nM, and also inhibits calpain with IC50 of 1.2 μM.A proteasome and NF-κB inhibitor.

MG-132 is an inhibitor of proteasome with IC50 of 100 nM, and also inhibits calpain with IC50 of 1.2 μM.A proteasome and NF-κB inhibitor.

MG-132 is an inhibitor of proteasome with IC50 of 100 nM, and also inhibits calpain with IC50 of 1.2 μM.A proteasome and NF-κB inhibitor.

MG-132 is an inhibitor of proteasome with IC50 of 100 nM, and also inhibits calpain with IC50 of 1.2 μM.A proteasome and NF-κB inhibitor.

Amino Acid Sequence Z-Leu-Leu-Leu-al General description A potent, reversible, and cell-permeable proteasome inhibitor (K i = 4 nM). Reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable strains of yeast by the

Amino Acid Sequence Z-Leu-Leu-Leu-al General description A potent, reversible, and cell-permeable proteasome inhibitor (K i = 4 nM). Reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable strains of yeast by the